Intrinsic excitability measures track antiepileptic drug action and uncover increasing/decreasing excitability over the wake/sleep cycle

Christian Meisel; Andreas Schulze-Bonhage; Dean Freestone; Mark James Cook; Peter Achermann; Dietmar Plenz

Journal article

Intrinsic excitability measures track antiepileptic drug action and uncover increasing/decreasing excitability over the wake/sleep cycle

Christian Meisel, Andreas Schulze-Bonhage, Dean Freestone, Mark James Cook, Peter Achermann, Dietmar Plenz

Proceedings of the National Academy of Sciences | NATL ACAD SCIENCES | Published : 2015

DOI: 10.1073/pnas.1513716112

University of Melbourne Researchers

Mark Cook Author Medicine - St Vincent's Hospital

Dean Freestone Author Medicine - St Vincent's Hospital

Related Projects (1)

Advanced Epileptic Seizure Warning Methods

Epilepsy is a debilitating neurological disorder characterised by spontaneous seizures. For a third of epilepsy patients, drugs cannot preve..

Grants

Awarded by National Institute of Mental Health

Awarded by Cluster of Excellence BrainLinks-BrainTools

Funding Acknowledgements

This study was supported by the Intramural Research Program of the National Institute of Mental Health (ZIAMH002797). This study used the high-performance computational capabilities of the Biowulf Linux cluster at the National Institutes of Health. A.S.-B. would like to acknowledge support by the Cluster of Excellence BrainLinks-BrainTools (EXC-1086).