Placental Insufficiency in Fetuses That Slow in Growth but Are Born Appropriate for Gestational Age: A Prospective Longitudinal Study
Nadia Bardien, Clare L Whitehead, Stephen Tong, Antony Ugoni, Susan McDonald, Susan P Walker
PLOS ONE | PUBLIC LIBRARY SCIENCE | Published : 2016
OBJECTIVES: To determine whether fetuses that slow in growth but are then born appropriate for gestational age (AGA, birthweight >10th centile) demonstrate ultrasound and clinical evidence of placental insufficiency. METHODS: Prospective longitudinal study of 48 pregnancies reaching term and a birthweight >10th centile. We estimated fetal weight by ultrasound at 28 and 36 weeks, and recorded birthweight to determine the relative change in customised weight across two timepoints: 28-36 weeks and 28 weeks-birth. The relative change in weight centiles were correlated with fetoplacental Doppler findings performed at 36 weeks. We also examined whether a decline in growth trajectory in fetuses bor..View full abstract
Related Projects (2)
Awarded by National Health and Medical Research Council
Awarded by Career Development Fellowship
Support was provided by the National Health and Medical Research Council: Project Grant 1065854 (to SW) and Career Development Fellowship 1050765 (to ST), and by the Medical Research Foundation for Women and Babies (to SW).