The march from early life food sensitization to allergic disease: a systematic review and meta-analyses of birth cohort studies
SA Alduraywish, CJ Lodge, B Campbell, KJ Allen, B Erbas, AJ Lowe, SC Dharmage
ALLERGY | WILEY | Published : 2016
BACKGROUND: There is growing evidence for an increase in food allergies. The question of whether early life food sensitization, a primary step in food allergies, leads to other allergic disease is a controversial but important issue. Birth cohorts are an ideal design to answer this question. OBJECTIVES: We aimed to systematically investigate and meta-analyse the evidence for associations between early food sensitization and allergic disease in birth cohorts. METHODS: MEDLINE and SCOPUS databases were searched for birth cohorts that have investigated the association between food sensitization in the first 2 years and subsequent wheeze/asthma, eczema and/or allergic rhinitis. We performed meta..View full abstract
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SA has scholarship from King Saud University, Riyadh-Saudi Arabia represented by Saudi Arabian Cultural Mission in Canberra-Australia; CL, AL and SD are funded by The National Health and Medical Research Council of Australia (NHMRC); KA is funded by the Charles and Sylvia Viertel Charitable Foundation; BE has no personal funding relationships to declare.