Strongly basic medium-ring diamines which mimic gas phase behaviour in solution: 1,6-Dimethyl-1,6-diazacyclodecane

Abstract

Monocyclic medium-ring diamines whose monoprotonated ions can form transannular hydrogen bonds have enhanced basicities in solution; structural data for 1,6-dimethyl-1,6-diazacyclodecane suggest that the enhanced basicity may reflect steric inhibition of solvation, leading to gas-phase-like behaviour.