Journal article

Influenza vaccine effectiveness against hospitalisation with influenza in adults in Australia in 2014

AC Cheng, T Kotsimbos, PM Kelly, P Wark, C Hunter, S Hewagama, ND Friedman, TM Korman, G Simpson, JW Upham, S Bowler, SJ Senenayake, M Holmes, L Irving, SGA Brown, G Waterer, DE Dwyer, K Macartney, C Blyth

Vaccine | ELSEVIER SCI LTD | Published : 2015

Abstract

We provide estimates of the influenza vaccine protection against hospitalisation with laboratory-confirmed influenza in the 2014 Australian season where the A/H1N1/pdm09 strain predominated. This was performed using a case-test negative study design as part of a national sentinel surveillance system in Australia. Vaccine effectiveness was estimated as (1-OR). ×. 100% where the odds ratio of vaccination in cases vs test negative participants was estimated from a conditional logistic regression. Between April and November, 1692 adult patients were admitted with laboratory-confirmed influenza. Vaccine effectiveness was estimated from 1283 patients with influenza and 1116 test negative patients ..

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University of Melbourne Researchers

Grants

Funding Acknowledgements

We thank Ellen MacDonald (Royal Perth Hospital), Rebecca Davis (The Mater Hospital Brisbane), Patricia King (Westmead Hospital), Sue Dixon, Sue Richmond (Cairns Base Hospital), Tina Collins, (Princess Alexandra Hospital), Wendy Beckingham, Sammy Xu (The Canberra Hospital), Mary McAlister, Louise Milazzo, Jenny McGrath (Royal Adelaide Hospital), Lorissa Hopkins, Douglas Dorahy (John Hunter Hospital), Susan Wagg (Royal Hobart Hospital), Michelle Thompson (Royal Melbourne Hospital), Janine Roney, Jill Garlick (The Alfred), Julie Heath, Jo Chambers (Geelong Hospital), Jocelynne McRae, Helen Knight, Sue Low, Sharon Tan, Laura Rost (Children's Hospital at Westmead) and Cazz Finucane, Jackie Connell (Princess Margaret Hospital). We acknowledge the support of the Australian Department of Health for funding this system.