Journal article

Activation of the erythroid K-Cl cotransporter Kcc1 enhances sickle cell disease pathology in a humanized mouse model

Fiona C Brown, Ashlee J Conway, Loretta Cerruti, Janelle E Collinge, Catriona McLean, James S Wiley, Ben T Kile, Stephen M Jane, David J Curtis

Blood | AMER SOC HEMATOLOGY | Published : 2015

DOI: 10.1182/blood-2014-10-609362

Grants

Awarded by Australian National Health and Medical Research Council

Funding Acknowledgements

This study was supported by a project grant (382900) from the Australian National Health and Medical Research Council (to S.M.J. and D.J.C.) and a Viertel Senior Medical Research fellowship (to D.J.C.).

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Keywords

Life Sciences & Biomedicine
Reticulocytes
Disease Models, Animal
Anemia, Sickle Cell
Animals
Mice
Mutation, Missense
Transport
Symporters
Humans
Mice, Inbred C57bl
Mice, Mutant Strains
Sad Mice
Science & Technology
Mice, Inbred Balb C
Hematology
Reverse Transcriptase Polymerase Chain Reaction
High-Throughput Nucleotide Sequencing
Volume