Heightened self-reactivity associated with selective survival, but not expansion, of naive virus-specific CD8( ) T cells in aged mice
Kylie M Quinn, Sophie G Zaloumis, Tania Cukalac, Wan-Ting Kan, Xavier YX Sng, Michiko Mirams, Katherine A Watson, James M McCaw, Peter C Doherty, Paul G Thomas, Andreas Handel, Nicole L La Gruta
Proceedings of the National Academy of Sciences | NATL ACAD SCIENCES | Published : 2016
Awarded by National Health and Medical Research Council (NHMRC)
Awarded by National Institutes of Health
Awarded by NHMRC Biomedical Postgraduate Scholarship
Awarded by NHMRC Centre of Research Excellence Grant
We thank Stephen J. Turner for critical reading of the manuscript. This work was supported by National Health and Medical Research Council (NHMRC) Program Grant AI1071916 (to P. C. D. and N. L. L. G.) and Project Grant AI1046333 (to N. L. L. G.), National Institutes of Health Grants U19AI117891 (to P. G. T. and A. H.) and AI107625 (to P. G. T.), a Sylvia and Charles Viertel Senior Medical Research Fellowship (to N. L. L. G.), an Australian Research Council Future Fellowship (to J. M. M.), and NHMRC Biomedical Postgraduate Scholarship AI520643 (to T. C.). S. G. Z. was supported under NHMRC Centre of Research Excellence Grant AI1035261, awarded to the Victorian Centre for Biostatistics (ViCBiostat).