Primary Tumor Resection and Overall Survival in Patients With Metastatic Colorectal Cancer Treated With Palliative Intent

Abstract

The present study examined the effect of primary tumor resection on overall survival of patients with metastatic colorectal cancer (mCRC). A total of 690 de novo and 373 metachronous mCRC patients treated with palliative intent were identified. For patients with de novo mCRC, primary tumor resection at diagnosis does not significantly improve overall survival when adjusting for known major prognostic factors. Background The survival impact of primary tumor resection in patients with metastatic colorectal cancer (mCRC) treated with palliative intent remains uncertain. In the absence of randomized data, the objectives of the present study were to examine the effect of primary tumor resection (..