Journal article
Heterogeneity of psychosis risk within individuals at clinical high risk: A meta-analytical stratification
P Fusar-Poli, M Cappucciati, S Borgwardt, SW Woods, J Addington, B Nelson, DH Nieman, DR Stahl, G Rutigliano, A Riecher-Rössler, AE Simon, M Mizuno, TY Lee, JS Kwon, MML Lam, J Perez, S Keri, P Amminger, S Metzler, W Kawohl Show all
JAMA Psychiatry | Published : 2016
Abstract
IMPORTANCE Individuals can be classified as being at clinical high risk (CHR) for psychosis if they meet at least one of the ultra-high-risk (UHR) inclusion criteria (brief limited intermittent psychotic symptoms [BLIPS] and/or attenuated psychotic symptoms [APS] and/or genetic risk and deterioration syndrome [GRD]) and/or basic symptoms [BS]. Themeta-analytical risk of psychosis of these different subgroups is still unknown. OBJECTIVE To compare the risk of psychosis in CHR individuals who met at least one of the major inclusion criteria and in individuals not at CHR for psychosis (CHR-). DATA SOURCES Electronic databases (Web of Science, MEDLINE, Scopus) were searched until June 18, 2015, ..
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Awarded by National Institutes of Health
Funding Acknowledgements
This study was supported in part by a 2014 NARSAD Young Investigator Award (Dr Fusar-Poli). The research leading to these results has also received funding from the European Community's Seventh Framework Programme under grant agreement HEALTH-F2-2013-603196 (Project PSYSCAN [Translating Neuroimaging Findings from Research into Clinical Practice]).