Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma
Karen M Mann, Jerrold M Ward, Christopher Chin Kuan Yew, Anne Kovochich, David W Dawson, Michael A Black, Benjamin T Brett, Todd E Sheetz, Adam J Dupuy, David K Chang, Andrew V Biankin, Nicola Waddell, Karin S Kassahn, Sean M Grimmond, Alistair G Rust, David J Adams, Nancy A Jenkins, Neal G Copeland
Proceedings of the National Academy of Sciences | NATL ACAD SCIENCES | Published : 2012
Awarded by Cancer Research UK
The authors thank Keith Rogers, Susan Rogers, and the Institute for Molecular and Cell Biology Histopathology Core. We thank Doug Melton for the Pdx1-Cre animals and Angela Chou, Anatomical Pathologist at the Garvan Institute of Medical Research, for performing the second blinded scoring for the tissue microarray. We also acknowledge Pearlyn Cheok, Nicole Lim, and Dorothy Chen for their help with tumor monitoring. This work was supported in part by the Biomedical Research Council, Agency for Science, Technology, and Research, Singapore; the National Health and Medical Research Council of Australia; the Queensland Government; the Cancer Council New South Wales; the Cancer Institute New South Wales; the Royal Australian College of Surgeons; the Australian Cancer Research Foundation; the St. Vincent's Clinic Foundation; the Avner Nahmani Pancreatic Cancer Foundation; and the R. T. Hall Trust.