Journal article
Expression of a novel mammalian epidermal growth factor-related gene during mouse neural development
S Grimmond, R Larder, N Van Hateren, P Siggers, S Morse, T Hacker, R Arkell, A Greenfield
Mechanisms of Development | ELSEVIER SCIENCE BV | Published : 2001
Abstract
We have recently reported the preliminary characterisation of a novel EGF-related gene, Scube1 (signal peptide-CUB domain-EGF-related, gene 1), that is expressed prominently in the developing gonad, nervous system, somites, surface ectoderm and limb buds of the mouse. Here we describe the expression pattern of a closely related gene, Scube2 (also known as Cegp1), which maps to the distal region of mouse chromosome 7. Scube2 transcription is restricted to the embryonic neurectoderm but is also detectable in the adult heart, lung and testis. Copyright © 2001 Elsevier Science Ireland Ltd.
Grants
Awarded by MRC
Awarded by Medical Research Council