Journal article

Versatile Loading of Diverse Cargo into Functional Polymer Capsules

Joseph J Richardson, James W Maina, Hirotaka Ejima, Ming Hu, Junling Guo, Mei Y Choy, Sylvia T Gunawan, Lien Lybaert, Christoph E Hagemeyer, Bruno G De Geest, Frank Caruso

ADVANCED SCIENCE | WILEY | Published : 2015

Abstract

Polymer microcapsules are of particular interest for applications including self-healing coatings, catalysis, bioreactions, sensing, and drug delivery. The primary way that polymer capsules can exhibit functionality relevant to these diverse fields is through the incorporation of functional cargo in the capsule cavity or wall. Diverse functional and therapeutic cargo can be loaded into polymer capsules with ease using polymer-stabilized calcium carbonate (CaCO3) particles. A variety of examples are demonstrated, including 15 types of cargo, yielding a toolbox with effectively 500+ variations. This process uses no harsh reagents and can take less than 30 min to prepare, load, coat, and form t..

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Grants

Awarded by Australian Research Council (ARC)


Awarded by ARC Centre of Excellence in Convergent Bio-Nano Science and Technology


Funding Acknowledgements

We acknowledge Blaise Tardy, Henk Dam, Kristian Kempe, Jiwei Cui, Kang Liang, Yuan Ping, Olga Shimoni, Shota Sekiguchi, and Shen Tay for contribution of materials. This research was supported by the Australian Research Council (ARC) under the Australian Laureate Fellowship (F.C., FL120100030) and the Super Science Fellowship (F.C., FS110200025) schemes. This research was conducted and funded in part by the ARC Centre of Excellence in Convergent Bio-Nano Science and Technology (Project No. CE140100036).