Associations of surgical and nonsurgical weight loss with knee musculature: A cohort study of obese adults

Abstract

Background: Marked weight loss reduces lean body mass and quadriceps thickness. It is unclear whether muscle loss varies according to the method of weight loss. Objective: This study compared the association of surgical versus nonsurgical weight loss with change in vastus medialis (VM) properties in obese adults. Methods: Twenty obese patients (body mass index Z30 kg/m2) who lost weight via laparoscopic gastric banding were matched for weight loss with obese patients who lost weight nonsurgically. The thickness and fat infiltration of VM were assessed at baseline and a mean of 2.4 years later. Results: After adjusting for confounders, the annual change in VM thickness was -2.9% in the surgic..