Journal article
Childhood body mass index and adult mammographic density measures that predict breast cancer risk
JL Hopper, TL Nguyen, J Stone, K Aujard, MC Matheson, MJ Abramson, JA Burgess, EH Walters, GS Dite, M Bui, C Evans, E Makalic, DF Schmidt, G Ward, MA Jenkins, GG Giles, SC Dharmage, C Apicella
Breast Cancer Research and Treatment | Published : 2016
Abstract
The aim of the present study is to determine if body mass index (BMI) during childhood is associated with the breast cancer risk factor ‘adult mammographic density adjusted for age and BMI’. In 1968, the Tasmanian Longitudinal Health Study studied every Tasmanian school child born in 1961. We obtained measured heights and weights from annual school medical records across ages 7–15 years and imputed missing values. Between 2009 and 2012, we administered to 490 women a questionnaire that asked current height and weight and digitised at least one mammogram per woman. Absolute and percent mammographic densities were measured using the computer-assisted method CUMULUS. We used linear regression a..
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Funding Acknowledgements
This study was funded by the National Health and Medical Research Council of Australia.