Journal article

Clinical significance not statistical significance: a simple Bayesian alternative to p values

PR Burton, LC Gurrin, MJ Campbell

JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH | BMJ PUBLISHING GROUP | Published : 1998

Abstract

OBJECTIVES: To take the common "Bayesian" interpretation of conventional confidence intervals to its logical conclusion, and hence to derive a simple, intuitive way to interpret the results of public health and clinical studies. DESIGN AND SETTING: The theoretical basis and practicalities of the approach advocated is at first explained and then its use is illustrated by referring to the interpretation of a real historical cohort study. The study considered compared survival on haemodialysis (HD) with that on continuous ambulatory peritoneal dialysis (CAPD) in 389 patients dialysed for end stage renal disease in Leicestershire between 1974 and 1985. Careful interpretation of the study was ess..

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