High fidelity simian immunodeficiency virus reverse transcriptase mutants have impaired replication in vitro and in vivo

Sarah B Lloyd; Marit Lichtfuss; Thakshila H Amarasena; Sheilajen Alcantara; Robert De Rose; Gilda Tachedjian; Hamid Alinejad-Rokny; Vanessa Venturi; Miles P Davenport; Wendy R Winnall; Stephen J Kent

Journal article

High fidelity simian immunodeficiency virus reverse transcriptase mutants have impaired replication in vitro and in vivo

Sarah B Lloyd, Marit Lichtfuss, Thakshila H Amarasena, Sheilajen Alcantara, Robert De Rose, Gilda Tachedjian, Hamid Alinejad-Rokny, Vanessa Venturi, Miles P Davenport, Wendy R Winnall, Stephen J Kent

Virology | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2016

DOI: 10.1016/j.virol.2016.02.008

University of Melbourne Researchers

Stephen Kent Author Microbiology and Immunology

Rob De Rose Author Chemical Engineering

Grants

Awarded by Australian NHMRC Fellowships

Awarded by NHMRC Program

Funding Acknowledgements

We thank Dr. Robert Center, Prof Damian Purcell and Dr. Keith Peden for SIV reagents and Sushama Telwatte for expert advice. This work was supported by Australian NHMRC Fellowships (1013221 to WRW and 1041832 to SJK), NHMRC Program grant 510448 and an Early Career Researcher grant from the University of Melbourne.