Journal article

A combination of physical activity and computerized brain training improves verbal memory and increases cerebral glucose metabolism in the elderly

T Shah, G Verdile, H Sohrabi, A Campbell, E Putland, C Cheetham, S Dhaliwal, M Weinborn, P Maruff, D Darby, RN Martins



Physical exercise interventions and cognitive training programs have individually been reported to improve cognition in the healthy elderly population; however, the clinical significance of using a combined approach is currently lacking. This study evaluated whether physical activity (PA), computerized cognitive training and/or a combination of both could improve cognition. In this nonrandomized study, 224 healthy community-dwelling older adults (60-85 years) were assigned to 16 weeks home-based PA (n=64), computerized cognitive stimulation (n=62), a combination of both (combined, n=51) or a control group (n=47). Cognition was assessed using the Rey Auditory Verbal Learning Test, Controlled ..

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Funding Acknowledgements

TS is supported by the Australian Postgraduate Award from the University of Western Australia, the Research Excellence Award form Edith Cowan University and the Freemasons of Western Australia Education Grant 2010 and 2011. The McCusker Alzheimer's Research Foundation contributed financial and in-kind support for the study. Posit Science (San Francisco, CA, USA) has generously provided us their software programs for the study. We thank all the study participants for their time, commitment and dedication for this intervention study and also the research staff at the Foundation.