Cerebral palsy: Effects of twinning, birthweight, and gestational age

Abstract

Aims - To determine the effects of birthweight and gestational age on the risk of cerebral palsy for multiple and singleton births. Methods - Children on the North East Thames Regional Health Authority Interactive Child Health System, born between 1 January 1980 and 31 December 1986, and notified as having cerebral palsy, were included. Cases of postneonatal onset, of known progressive, or non-cerebral pathology and with only mild signs were excluded. Rates and relative risks were calculated using the most complete data, which related to 1985-86, and comprised 102 059 singletons and 2367 twins. Logistic regression was used to examine the associations between being a twin, gestational age, an..