Journal article

RADBIOMOD: A simple program for utilising biological modelling in radiotherapy plan evaluation

Joe H Chang, Christopher Gehrke, Ramachandran Prabhakar, Suki Gill, Morikatsu Wada, Daryl Lim Joon, Vincent Khoo

Physica Medica | ELSEVIER SCI LTD | Published : 2016

Abstract

PURPOSE: Radiotherapy plan evaluation is currently performed by assessing physical parameters, which has many limitations. Biological modelling can potentially allow plan evaluation that is more reflective of clinical outcomes, however further research is required into this field before it can be used clinically. METHODS: A simple program, RADBIOMOD, has been developed using Visual Basic for Applications (VBA) for Microsoft Excel that incorporates multiple different biological models for radiotherapy plan evaluation, including modified Poisson tumour control probability (TCP), modified Zaider-Minerbo TCP, Lyman-Kutcher-Burman normal tissue complication probability (NTCP), equivalent uniform ..

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University of Melbourne Researchers