Journal article
Primary antifungal prophylaxis in adult patients with acute lymphoblastic leukaemia: A multicentre audit
TN Doan, CMJ Kirkpatrick, P Walker, MA Slavin, MR Ananda-Rajah, CO Morrissey, KF Urbancic, A Grigg, A Spencer, J Szer, JF Seymour, DCM Kong
Journal of Antimicrobial Chemotherapy | OXFORD UNIV PRESS | Published : 2016
DOI: 10.1093/jac/dkv343
Abstract
Objectives: The primary objectives were to investigate the prescribing practices of primary antifungal prophylaxis (PAP) and incidence of invasive fungal disease (IFD) in adult patients with ALL receiving induction-consolidation chemotherapy. Secondary objectives were to determine risk factors for IFD and resource utilization associated with IFD. Methods: A retrospective chart review of adult patients with ALL from commencement of induction until completion of consolidation chemotherapy was undertaken from January 2008 to June 2013 in four hospitals in Melbourne, Australia. IFD was classified according to the revised European Organisation for Research and Treatment of Cancer criteria. Cost a..
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Funding Acknowledgements
This study was supported by the Monash Graduate Scholarship and Monash International Postgraduate Research Scholarship granted to T. N. D.