Journal article
“Cancer 2015”: A prospective, population-based cancer cohort—phase 1: Feasibility of genomics-guided precision medicine in the clinic
JP Parisot, H Thorne, A Fellowes, K Doig, M Lucas, JJ McNeil, B Doble, A Dobrovic, T John, PA James, L Lipton, D Ashley, T Hayes, P McMurrick, G Richardson, P Lorgelly, SB Fox, DM Thomas
Journal of Personalized Medicine | Published : 2015
DOI: 10.3390/jpm5040354
Abstract
“Cancer 2015” is a longitudinal and prospective cohort. It is a phased study whose aim was to pilot recruiting 1000 patients during phase 1 to establish the feasibility of providing a population-based genomics cohort. Newly diagnosed adult patients with solid cancers, with residual tumour material for molecular genomics testing, were recruited into the cohort for the collection of a dataset containing clinical, molecular pathology, health resource use and outcomes data. 1685 patients have been recruited over almost 3 years from five hospitals. Thirty-two percent are aged between 61–70 years old, with a median age of 63 years. Diagnostic tumour samples were obtained for 90% of these patients ..
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Funding Acknowledgements
We would like to sincerely thank all the cancer patients who agreed to participate in the cohort. We acknowledge the contributions of the following staff and collaborators of this multi-site cohort: Kristy Barnes-Cullen, Kate Crough, Jessica McDonald, Kim Waddell, Jasmine Marr, Mandy Ballinger, Ann Officer, Anne Fennessy, Sonia Mailer, Connie Mascarenhas and Mathew Shibi from the Peter MacCallum Cancer Centre; Kate Richards, Laura Zamurs and Kate Hurford from Cabrini Health; Carolyn Wielens, Lea-Anne Harrison, Judi Broad, Robert Swiger, Tina Smith and Anne Woollett from The Andrew Love Cancer Centre, Barwon Health; Sandra Robinson and Marcelle Hennig from SouthWest Health; Monica Merceica, Stefanie Hartley, Pat Bugeja, Lidia Veca, Christopher Bates and Nicole Ng from The Royal Melbourne Hospital, Melbourne Health; Neil Watkins from Monash Medical Centre, Southern Health; Paul Waring and Melissa Southey from the Department of Pathology, University of Melbourne. We also acknowledge the contributions of the Cancer 2015 Expert Advisory Committee consisting of Richard Sullivan, John Zalcberg, Andrew Biankin, Sean Grimmond, David Roder and David Goldstein and last but not least, Pamela Williams as our valued Consumer Advocate for the Steering Committee chaired by Michael Wright. The Olivia Newton-John Cancer Research Institute acknowledges the support of the Victorian Government Operational and Infrastructure Support Program. This study was supported by the Victorian Government through the Victorian Cancer Agency Translational Research Program.