Metformin as a prevention and treatment for preeclampsia: effects on soluble fms-like tyrosine kinase 1 and soluble endoglin secretion and endothelial dysfunction

Fiona C Brownfoot; Roxanne Hastie; Natalie J Hannan; Ping Cannon; Laura Tuohey; Laura J Parry; Sevvandi Senadheera; Sebastian E Illanes; Tu'uhevaha J Kaitu'u-Lino; Stephen Tong

Journal article

Metformin as a prevention and treatment for preeclampsia: effects on soluble fms-like tyrosine kinase 1 and soluble endoglin secretion and endothelial dysfunction

Fiona C Brownfoot, Roxanne Hastie, Natalie J Hannan, Ping Cannon, Laura Tuohey, Laura J Parry, Sevvandi Senadheera, Sebastian E Illanes, Tu'uhevaha J Kaitu'u-Lino, Stephen Tong

American Journal of Obstetrics and Gynecology | MOSBY-ELSEVIER | Published : 2016

DOI: 10.1016/j.ajog.2015.12.019

University of Melbourne Researchers

Tu'uhevaha Lino Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Roxanne Hastie Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Stephen Tong Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Fiona Brownfoot Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Ping Cannon Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Related Projects (1)

Soluble endoglin in the pathogenesis of preeclampsia: investigation of mechanisms and the development of therapeutics

Preeclampsia is a severe disease of pregnancy. As the pathogenesis is poorly understood, the only treatment is for clinicians to deliver bab..

Grants

Awarded by National Health and Medical Research Council of Australia (NHMRC)

Awarded by NHMRC

Funding Acknowledgements

Supported by The National Health and Medical Research Council of Australia (NHMRC; #1048707, #1046484, #1101871) and an Arthur Wilson RANZCOG scholarship; by an Australian Postgraduate Award and an AVANT scholarship (F.B); by a CR Roper Research Fellowship (N.J.R.); the NHMRC provided salary support (#1050765 [S.T.]; #1062418 [T.K.L.]; #628549 [S.S.]). The funders had no role in study design, data collection, analysis, decision to publish or the preparation of the manuscript.