Image guidance and stabilization for stereotactic ablative body radiation therapy (SABR) treatment of primary kidney cancer

Abstract

Purpose: Stereotactic ablative body radiation therapy for primary kidney cancer treatment relies on motion management that can quantify both the trajectory of kidney motion and stabilize the patient. A prospective ethics-approved clinical trial of stereotactic treatment to primary kidney targets was conducted at our institution. Our aim was to report on specific kidney tumor motion and the inter- and intrafraction motion as seen on treatment. Methods and materials: Patients with tumor size < 5 cm received a dose of 26 Gy in 1 fraction and those with tumor size ≥ 5 cm received 42 Gy in 3 fractions. All patients underwent a 4-dimensional computed tomography planning scan, immobilized in a dual..