Bacterial interactions in pathogenic subgingival plaque
Hong Min Ng, Lin Xin Kin, Stuart G Dashper, Nada Slakeski, Catherine A Butler, Eric C Reynolds
MICROBIAL PATHOGENESIS | ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD | Published : 2016
Chronic periodontitis has a polymicrobial biofilm aetiology. Polymicrobial biofilms are complex, dynamic microbial communities formed by two or more bacterial species that are important for the persistence and proliferation of participating microbes in the environment. Interspecies adherence, which often involves bacterial surface-associated molecules, and communications are essential in the spatial and temporal development of a polymicrobial biofilm, which in turn is necessary for the overall fitness of a well-organized multispecies biofilm community. In the oral cavity, interactions between key oral bacterial species, including Porphyromonas gingivalis, Treponema denticola and Tannerella f..View full abstract
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Awarded by Australian National Health and Medical Research Council
This work was supported by the Australian National Health and Medical Research Council (Project Grant No. 1083600). Dr. Kheng Hui Tan is thanked for provision of the figure demonstrating coaggregation of P. gingivalis and T. denticola. Mr. Chris Owen is thanked for assistance with figure preparation. Dr. Ying Zhu, Ms. Deanne Catmull and Dr. Tanya D'Cruze are thanked for assistance with the flow cell set up and confocal imaging of the biofilms in Fig. 1. Lin Xin Kin is supported by a Melbourne International Research Scholarship funded by the University of Melbourne. Ng Hong Min is supported by an International Postgraduate Research Scholarship funded by the Australian Government under the University of Melbourne.