The Performance of Anal Cytology as a Screening Test for Anal HSILs in Homosexual Men
Fengyi Jin, Andrew E Grulich, I Mary Poynten, Richard J Hillman, David J Templeton, Carmella LH Law, Annabelle Farnsworth, Suzanne M Garland, Christopher K Fairley, Jennifer M Roberts
CANCER CYTOPATHOLOGY | WILEY | Published : 2016
BACKGROUND: Studies regarding the performance of anal cytology in which both the screening test (cytology) and the diagnostic test (high-resolution anoscopy [HRA]) are performed in all members of a screening population are rare. The authors evaluated the performance of liquid-based anal cytology in a cohort of homosexual men in Sydney, New South Wales, Australia. METHODS: The Study of the Prevention of Anal Cancer (SPANC) is a 3-year prospective study of the natural history of anal human papillomavirus infection in homosexual men aged ≥35 years. At baseline, all participants underwent a liquid-based anal cytology test and HRA at the same clinical visit. Biopsies were obtained for histologica..View full abstract
Awarded by National Health and Medical Research Council
Awarded by Cancer Council NSW Strategic Research Partnership Program
The Study of the Prevention of Anal Cancer is funded by a National Health and Medical Research Council program grant (568971) and a Cancer Council NSW Strategic Research Partnership Program grant (13-11). Cytological testing materials were provided by Hologic (Australia) Pty Ltd. Andrew E. Grulich (grant 1081175), I. Mary Poynten (grant 1016307), and David J. Templeton (grant 1013353) were supported by fellowships from the National Health and Medical Research Council. The Kirby Institute is affiliated with the Faculty of Medicine of the University of New South Wales and funded by the Australian Government Department of Health and Ageing. The views expressed in this publication do not necessarily represent the position of the Australian Government.