Temporal changes of antibiotic-resistance genes and bacterial communities in two contrasting soils treated with cattle manure
Hang-Wei Hu, Xue-Mei Han, Xiu-Zhen Shi, Jun-Tao Wang, Li-Li Han, Deli Chen, Ji-Zheng He
FEMS MICROBIOLOGY ECOLOGY | OXFORD UNIV PRESS | Published : 2016
The emerging environmental spread of antibiotic-resistance genes (ARGs) and their subsequent acquisition by clinically relevant microorganisms is a major threat to public health. Animal manure has been recognized as an important reservoir of ARGs; however, the dissemination of manure-derived ARGs and the impacts of manure application on the soil resistome remain obscure. Here, we conducted a microcosm study to assess the temporal succession of total bacteria and a broad spectrum of ARGs in two contrasting soils following manure application from cattle that had not been treated with antibiotics. High-capacity quantitative PCR detected 52 unique ARGs across all the samples, with β-lactamase as..View full abstract
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Awarded by Chinese Academy of Sciences
Awarded by Australian Research Council
This work was financially supported by Melbourne Early Career Researcher Grant Scheme, Chinese Academy of Sciences (XDB15020200), and Australian Research Council (DE150100870).