Journal article
Continuous and Dichotomous Metabolic Syndrome Definitions in Youth Predict Adult Type 2 Diabetes and Carotid Artery Intima Media Thickness: The Cardiovascular Risk in Young Finns Study
CG Magnussen, S Cheriyan, MA Sabin, M Juonala, J Koskinen, R Thomson, MR Skilton, M Kähönen, T Laitinen, L Taittonen, N Hutri-Kähönen, JSA Viikari, OT Raitakari
Journal of Pediatrics | Published : 2016
Abstract
Objectives To examine the utility of continuous metabolic syndrome (cMetS) scores vs a dichotomous metabolic syndrome (MetS) definition in youth to predict adult type 2 diabetes mellitus (T2DM) and carotid intima-media thickness (IMT). Study design Participants (n = 1453) from the population-based, prospective, observational Cardiovascular Risk in Young Finns Study who were examined in youth (when aged 9-18 years) and re-examined 15-25 years later. Four cMetS scores were constructed according to procedures most often used in the literature that comprised the youth risk factor inputs of body mass index, blood pressure, glucose, insulin, high-density lipoprotein-cholesterol, and triglycerides...
View full abstractGrants
Awarded by National Health and Medical Research Council
Funding Acknowledgements
The Cardiovascular Risk in Young Finns Study is supported by the Academy of Finland (126925, 121584, 124282, 129378, 117797, and 41071), the Social Insurance Institution of Finland, Kuopio, Tampere and Turku University Hospital Medical (9M048 and 9N035), Juho Vainio Foundation, Paavo Nurmi Foundation, Finnish Foundation for Cardiovascular Research, Finnish Cultural Foundation. C.M. and M.S. are supported by a National Health and Medical Research Council Early Career Fellowship (APP1037559 and APP1012201, respectively). M.S. also is supported through a National Health and Medical Research Council Career Development Fellowship (1004474). The authors declare no conflicts of interest.