Journal article
The influence of sterilization on nitrogen-included ultrananocrystalline diamond for biomedical applications
W Tong, PA Tran, AM Turnley, M Aramesh, S Prawer, M Brandt, K Fox
Materials Science and Engineering C | Published : 2016
Abstract
Diamond has shown great potential in different biomedical applications, but the effects of sterilization on its properties have not been investigated. Here, we studied the influence of five sterilization techniques (solvent cleaning, oxygen plasma, UV irradiation, autoclave and hydrogen peroxide) on nitrogen-included ultrananocrystalline diamond. The chemical modification of the diamond surface was evaluated using X-ray photoelectron spectroscopy and water contact angle measurements. Different degrees of surface oxidation and selective sp2 bonded carbon etching were found following all sterilization techniques, resulting in an increase of hydrophilicity. Higher viabilities of in vitro mouse ..
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Awarded by Australian Research Council
Funding Acknowledgements
The authors wish to acknowledge the Electron Microscopy facilities in Bio 21 Institute. The authors also thank Dimitra Stathopoulos from the Bionics Institute for her work with the Sterrad sterilization, the Royal Victorian Eye and Ear hospital for allowing access to their Sterrad facilities and Javad Jafari for his help with autoclaving some of the samples. This work was supported by the Australian Research Council (ARC) through its Special Research Initiative (SRI) in Bionic Vision Science and Technology grant to Bionic Vision Australia (BVA). AMT is supported by NH & MRC Research Fellowship (628344). The authors acknowledge the facilities, and the scientific and technical assistance of the RMIT University's Microscopy & Microanalysis Facility, a linked laboratory of the Australian Microscopy & Microanalysis Research Facility.