Journal article

Is There a Role for the ThinPrep Imaging System in Reporting Anal Cytology?

Jennifer Margaret Roberts, Fengyi Jin, Deborah Ekman, Marjorie Kay Adams, Ross Lindsay McDonald, Julia Kathleen Thurloe, Adele Richards, Isobel Mary Poynten, Carmella Law, Christopher Kincaid Fairley, Richard John Hillman, Sepehr N Tabrizi, Alyssa Marie Cornall, David James Templeton, Suzanne Marie Garland, Andrew Edwin Grulich, Annabelle Farnsworth



BACKGROUND: The ThinPrep Imaging System (TIS) is an accurate time-saving method of reading cervical ThinPrep slides in screening programs. As anal and cervical cytology are morphologically similar, TIS can potentially be used for anal cytology. We assessed the performance of TIS on anal ThinPrep slides from homosexual men in a natural history study of human papillomavirus-related anal abnormalities. METHODS: Four hundred nineteen anal cytology slides were processed by TIS and classified by a cytologist as either No further review (slide archived) or Manual review (slide requiring full manual screen). The results were compared with the original manual screening report for all slides and speci..

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