A genome scale RNAi screen identifies GLI1 as a novel gene regulating vorinostat sensitivity
KJ Falkenberg, A Newbold, CM Gould, J Luu, JA Trapani, GM Matthews, KJ Simpson, RW Johnstone
Cell Death & Differentiation | NATURE PUBLISHING GROUP | Published : 2016
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Awarded by Australian National Health and Medical Research Council (NHMRC)
We thank Richard Tothill, Maria Doyle and Jason Ellul for constructive discussions about NGS methodologies and analysis. For technical support, we also thank Yanny Handoko and Daniel Thomas (Victorian Centre for Functional Genomics), Andrea Newbold and Timothy Semple, Timothy Holloway and Aga Borcz (Molecular Genomics Facility). This work was supported by Merck Research Laboratories, and an Australian National Health and Medical Research Council (NHMRC) project grant APP1028871 (to RWJ). KJF was a recipient of an Australian Postgraduate Award and later a Cancer Council Victoria Postdoctoral Research Fellowship. RWJ is a Senior Principal Research Fellow of the National Health and Medical Research Council (NHMRC) of Australia and supported by NHMRC Program and Project Grants, Cancer Council Victoria, the Leukemia Foundation of Australia and the Victorian Cancer Agency. The VCFG (KJS) is funded by the Australian Cancer Research Foundation (ACRF), the Victorian Department of Industry, Innovation and Regional Development (DIIRD), the Australian Phenomics Network (APN) supported by funding from the Australian Government's Education Investment Fund through the Super Science Initiative, the Australasian Genomics Technologies Association (AMATA), the Brockhoff Foundation and the Peter MacCallum Cancer Centre Foundation.