Journal article

PUMA promotes apoptosis of hematopoietic progenitors driving leukemic progression in a mouse model of myelodysplasia

AA Guirguis, CI Slape, LM Failla, J Saw, CS Tremblay, DR Powell, F Rossello, A Wei, A Strasser, DJ Curtis

Cell Death & Differentiation | NATURE PUBLISHING GROUP | Published : 2016


Awarded by Australian National Health and Medical Research Council (NHMRC)

Awarded by NHMRC

Awarded by Leukemia and Lymphoma society

Awarded by NHMRC SPRF fellowship

Funding Acknowledgements

We thank Dr J Adams for providing mouse strains; S Beeraka for technical assistance; N Borg and K Spark for animal husbandry and the AMREP Flow Cytometry Core facility for its assistance with flow analysis and cell sorting. This study was supported by project grants from the Australian National Health and Medical Research Council (NHMRC) (628367) and Cancer Council Victoria awarded to CIS and DJC; a Viertel Senior Medical Research Fellowship awarded to DJC; a Leukaemia Foundation Clinical PhD Scholarship awarded to AAG; project grants from the NHMRC (1016701), Leukemia and Lymphoma society (700113), Cancer Council Victoria, an NHMRC SPRF fellowship (1020363) and the estate of Anthony (Toni) Redstone OAM awarded to AS.