Journal article
Changes in Quality of Life Associated with Complications of Diabetes: Results from the ADVANCE Study
Alison Hayes, Hisatomi Arima, Mark Woodward, John Chalmers, Neil Poulter, Pavel Hamet, Philip Clarke
VALUE IN HEALTH | ELSEVIER SCIENCE INC | Published : 2016
Abstract
OBJECTIVE: To measure the impact of complications on summary measures of health-related quality of life among people with type 2 diabetes. METHODS: Patients participating in the Action in Diabetes and Vascular Disease:Preterax and Diamicron MR Controlled Evaluation (ADVANCE) trial were administered a health-related quality-of-life questionnaire, the three-level EuroQol five-dimensional questionnaire (EQ-5D-3L), on four occasions over a 5-year period. We used two-way fixed-effects longitudinal regression models to investigate the impact of incident diabetes complications (stroke, heart failure, myocardial infarction, ischemic heart disease, renal failure, blindness, and amputation) on EQ-5D-3..
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Awarded by National Health and Medical Research Council of Australia (NHMRC)
Awarded by NHMRC
Funding Acknowledgements
This study was supported by the National Health and Medical Research Council of Australia (NHMRC) (project grant 571372). The ADVANCE trial (clinical trial reg. no. NCT00145925, clinicaltnals.gov) was partially funded by the NHMRC (project grant ID 211086 and program grants 358395 and 571281) and by Servier International.