Metabolomics, standards, and metabolic modeling for synthetic biology in plants
Camilla Beate Hill, Tobias Czauderna, Matthias Klapperstuck, Ute Roessner, Falk Schreiber
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY | FRONTIERS MEDIA SA | Published : 2015
Life on earth depends on dynamic chemical transformations that enable cellular functions, including electron transfer reactions, as well as synthesis and degradation of biomolecules. Biochemical reactions are coordinated in metabolic pathways that interact in a complex way to allow adequate regulation. Biotechnology, food, biofuel, agricultural, and pharmaceutical industries are highly interested in metabolic engineering as an enabling technology of synthetic biology to exploit cells for the controlled production of metabolites of interest. These approaches have only recently been extended to plants due to their greater metabolic complexity (such as primary and secondary metabolism) and high..View full abstract
UR and CH are funded through an Australian Research Council Future Fellowship program and are also grateful to the Victorian Node of Metabolomics Australia, which is funded through Bioplatforms Australia Pty Ltd, a National Collaborative Research Infrastructure Strategy (NCRIS), 5.1 biomolecular platforms and informatics investment, and coinvestment from the Victorian State government and The University of Melbourne. The authors are grateful for financial support from EFI SynBio.