Journal article
Baseline quality of life predicts pelvic exenteration outcome
I Choy, JM Young, T Badgery-Parker, LM Masya, HL Shepherd, C Koh, AG Heriot, MJ Solomon
ANZ Journal of Surgery | Published : 2017
DOI: 10.1111/ans.13419
Abstract
Background: Recurrent rectal cancer affects a significant group of patients with no current consensus on management. This study investigated patients' quality of life (QoL) in the 12 months after pelvic exenteration. Method: Prospective cohort study with clinical and QoL data collected at baseline and 1, 3, 6, 9 and 12 months. QoL trajectories were modelled over 12 months from date of discharge using linear mixed models. Results: Of 117 patients, 93 underwent pelvic exenteration surgery, 24 did not. Thirty-day mortality was nil for both groups. For patients who had surgery, 15 (16%) died within 12 months of surgery compared with nine (38%) of the non-surgery group. Baseline QoL scores were h..
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Awarded by Cancer Australia
Funding Acknowledgements
This study was funded by Cancer Australia and the Cancer Council Australia through the Priority-driven Collaborative Cancer Research Scheme (PdCCRS). Professor Young is supported by the Cancer Institute NSW through an Academic Leader in Cancer Epidemiology grant (08-EPC_1-01). Dr Cherry Koh was supported by the Mitchell J Notaras Fellowship in Colorectal Surgery awarded by the University of Sydney in cooperation with the Training Board of Colorectal Surgery of the Colorectal Surgical Society of Australia and New Zealand. We acknowledge the contribution of Rachael Roberts, Tina Thorpe and Susan Buglar with patient recruitment and data collection.