Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells
Celine Souilhol, Christele Gonneau, Javier G Lendinez, Antoniana Batsivari, Stanislav Rybtsov, Heather Wilson, Lucia Morgado-Palacin, David Hills, Samir Taoudi, Jennifer Antonchuk, Suling Zhao, Alexander Medvinsky
Nature Communications | NATURE PUBLISHING GROUP | Published : 2016
Awarded by People Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme FP7 under REA grant
Awarded by Medical Research Council
We thank J. Verth, C. Manson and R. McInnis for assistance with mouse maintenance and breeding, C. Watt., C. Flockhart, C. Forrest and A. Dyer for irradiations, S. Monard, O. Rodriguez, F. Rossi and C. Cryer for cell sorting and B. Vernay for assistance with confocal microscopy. We thank S. Morrison for providing SCF-GFP reporter mice; V. Ribes and J. Briscoe for GBS-GFP reporter mice; H. Niwa for the plasmid pPBhCMV1-cHA-IRES-VenuspA and Dr Stephen Gould, Genentech for providing Shh antagonist HhAntag. We thank M. Cohen-Tannoudji, J. Davis, J. Easterbrook, A. McGarvey, M. Gehring, S. Gordon-Keylock, B. Gottgens, S. Lowell, J. Pimanda, A. Tsakiridis, L. Forrester, P. Travers and V. Wilson for helpful comments. This work was supported by LLR, BBSRC, MRC, Wellcome Trust and the People Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme FP7/2007-2013/under REA grant agreement no 317250.