Journal article

Computational models of populations of bacteria and lytic phage

Konrad Krysiak-Baltyn, Gregory JO Martin, Anthony D Stickland, Peter J Scales, Sally L Gras

CRITICAL REVIEWS IN MICROBIOLOGY | TAYLOR & FRANCIS LTD | Published : 2016

Abstract

The use of phages to control and reduce numbers of unwanted bacteria can be traced back to the early 1900s, when phages were explored as a tool to treat infections before the wide scale use of antibiotics. Recently, phage therapy has received renewed interest as a method to treat multiresistant bacteria. Phages are also widely used in the food industry to prevent the growth of certain bacteria in foods, and are currently being explored as a tool for use in bioremediation and wastewater treatment. Despite the large body of biological research on phages, relatively little attention has been given to computational modeling of the population dynamics of phage and bacterial interactions. The earl..

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