Computational models of populations of bacteria and lytic phage
Konrad Krysiak-Baltyn, Gregory JO Martin, Anthony D Stickland, Peter J Scales, Sally L Gras
CRITICAL REVIEWS IN MICROBIOLOGY | TAYLOR & FRANCIS LTD | Published : 2016
The use of phages to control and reduce numbers of unwanted bacteria can be traced back to the early 1900s, when phages were explored as a tool to treat infections before the wide scale use of antibiotics. Recently, phage therapy has received renewed interest as a method to treat multiresistant bacteria. Phages are also widely used in the food industry to prevent the growth of certain bacteria in foods, and are currently being explored as a tool for use in bioremediation and wastewater treatment. Despite the large body of biological research on phages, relatively little attention has been given to computational modeling of the population dynamics of phage and bacterial interactions. The earl..View full abstract
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Awarded by Australian Research Council
Awarded by ARC Dairy Innovation Hub
This work was funded by an Australian Research Council Linkage Grant (LP120100304) with input from Melbourne Water, South Australia Water and Water Corporation. Sally Gras and Greg Martin are supported by The ARC Dairy Innovation Hub (IH120100005). The authors would like to thank the anonymous journal reviewers for constructive comments.