Journal article

Behavioural response to combined insecticide and temperature stress in natural populations of Drosophila melanogaster

A Fournier-Level, A Neumann-Mondlak, RT Good, LM Green, JM Schmidt, C Robin



Insecticide resistance evolves extremely rapidly, providing an illuminating model for the study of adaptation. With climate change reshaping species distribution, pest and disease vector control needs rethinking to include the effects of environmental variation and insect stress physiology. Here, we assessed how both long-term adaptation of populations to temperature and immediate temperature variation affect the genetic architecture of DDT insecticide response in Drosophila melanogaster. Mortality assays and behavioural assays based on continuous activity monitoring were used to assess the interaction between DDT and temperature on three field-derived populations from climate extremes (Rale..

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Awarded by Human Frontier in Science Long Term Fellowship

Funding Acknowledgements

We would like to thank J. Schirriffs and A. A. Hoffmann for sharing flies collected in Tasmania and Queensland. We are also grateful to P. Batterham for sharing laboratory space and T. Perry for their help in setting up the Drosophila Activity Monitoring system. This work was funded by the Human Frontier in Science Long Term Fellowship LT000907/2012-L and the Early Career Research Grant from the Faculty of Science of the University of Melbourne to AFL. The authors declare no conflicting interest.