Journal article

Associations of Sarcopenic Obesity and Dynapenic Obesity with Bone Mineral Density and Incident Fractures Over 5-10 Years in Community-Dwelling Older Adults

David Scott, Sahan D Chandrasekara, Laura L Laslett, Flavia M Cicuttini, Peter R Ebeling, Graeme Jones

CALCIFIED TISSUE INTERNATIONAL | SPRINGER | Published : 2016

Abstract

The purpose of this study is to determine whether low muscle mass (sarcopenia) or strength (dynapenia), in the presence of obesity, are associated with increased risk for osteoporosis and non-vertebral fracture over 5-10 years in community-dwelling older adults. N = 1089 volunteers (mean ± SD age 62 ± 7 years; 51 % female) participated at baseline and 761 attended follow-up clinics (mean 5.1 ± 0.5 years later). Total body, total hip and spine BMD, and appendicular lean and total fat mass were assessed by DXA. Sarcopenic obesity and dynapenic obesity were defined as the lowest sex-specific tertiles for appendicular lean mass or lower-limb strength, respectively, and the highest sex-specific t..

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University of Melbourne Researchers

Grants

Funding Acknowledgements

This work was supported by the National Health and Medical Research Council of Australia, Arthritis Foundation of Australia, Tasmanian Community Fund, and University of Tasmania Institutional Research Grants Scheme. We gratefully acknowledge the efforts of the TASOAC participants and staff, particularly study coordinator Catrina Boon. GJ and LL acknowledge fellowships from the National Health and Medical Research Council of Australia.