Journal article

Development of a population pharmacokinetic-pharmacodynamic model of a single bolus dose of unfractionated heparin in paediatric patients

Hesham Al-Sallami, Fiona Newall, Paul Monagle, Vera Ignjatovic, Noel Cranswick, Stephen Duffull

British Journal of Clinical Pharmacology | WILEY-BLACKWELL | Published : 2016

DOI: 10.1111/bcp.12930

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Keywords

Paediatric
Dose-Response Relationship, Drug
Handling Data
Male
Children
Therapy
Science & Technology
Anticoagulants
Protamine
Life Sciences & Biomedicine
Time Factors
Unfractionated Heparin
Models, Biological
Adolescent
Pharmacology & Pharmacy
Aptt
Humans
Child
Ffm
Quantification Limit
Vs. Sequential-Analysis
Infants
Linear Models
Coronary Angiography
Likelihood Functions
Kinetics
Plasma
Partial Thromboplastin Time
Pkpd
Female
Heparin
Infant
Child, Preschool