Journal article

Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation

Marie-Claude Gingras, Kyle R Covington, David K Chang, Lawrence A Donehower, Anthony J Gill, Michael M Ittmann, Chad J Creighton, Amber L Johns, Eve Shinbrot, Ninad Dewal, William E Fisher, Christian Pilarsky, Robert Gruetzmann, Michael J Overman, Nigel B Jamieson, George Van Buren, Jennifer Drummond, Kimberly Walker, Oliver A Hampton, Liu Xi Show all

Cell Reports | CELL PRESS | Published : 2016

Grants

Awarded by HGSC-BCM: NHGRI


Awarded by CPRIT grant


Awarded by Dan L. Duncan Cancer Center NIH P30 Cancer Center


Awarded by Australian Pancreatic Cancer Genome Initiative: National Health and Medical Research Council of Australia (NHMRC)


Awarded by Cancer Research UK


Awarded by Cancer Council NSW


Awarded by Cancer Institute NSW


Awarded by Italian Ministry of Research


Awarded by Associazione Italiana Ricerca Cancro


Awarded by Fondazione Italiana Malattie Pancreas - Ministero Salute


Awarded by Wilhelm Sander Stiftung


Awarded by NIH


Awarded by Academy of Medical Sciences (AMS)


Awarded by Pancreatic Cancer UK


Funding Acknowledgements

We acknowledge the following funding support: HGSC-BCM: NHGRI U54 HG003273 and CPRIT grant RP101353-P7 (Tumor Banking for Genomic Research and Clinical Translation Site 1); D.W.A. CPRIT grant RPI21018; M.M.I. and C.J.C.: Dan L. Duncan Cancer Center NIH P30 Cancer Center support grant (P30 CA125123) supporting the BCM Human Tissue Acquisition and Pathology Core and the Biostatistics and Bioinformatics Core; M.J.O.: Kavanagh Family Foundation. Australian Pancreatic Cancer Genome Initiative: National Health and Medical Research Council of Australia (NHMRC; 631701, 535903, 427601); Queensland Government (NIRAP); University of Queensland; Institute for Molecular Bioscience; Cancer Research UK (C596/A18076, C29717/A17263); University of Glasgow; Australian Government: Department of Innovation, Industry, Science and Research (DIISR); Australian Cancer Research Foundation (ACRF); Cancer Council NSW: (SRP06-01, SRP11-01.ICGC); Cancer Institute NSW: (10/ECF/2-26; 06/ECF/1-24; 09/CDF/2-40; 07/CDF/1-03; 10/CRF/1-01, 08/RSA/1-15, 07/CDF/1-28, 10/CDF/2-26,10/FRL/2-03, 06/RSA/1-05, 09/RIG/1-02, 10/TPG/1-04, 11/REG/1-10, 11/CDF/3-26); Garvan Institute of Medical Research; Avner Nahmani Pancreatic Cancer Research Foundation; Howat Foundation; R.T. Hall Trust; Petre Foundation; Philip Hemstritch Foundation; Gastroenterological Society of Australia (GESA); American Association for Cancer Research (AACR) Landon Foundation - INNOVATOR Award; Royal Australasian College of Surgeons (RACS); Royal Australasian College of Physicians (RACP); Royal College of Pathologists of Australasia (RCPA); Italian Ministry of Research (Cancer Genome Project FIRB RBAP10AHJB); Associazione Italiana Ricerca Cancro (12182); Fondazione Italiana Malattie Pancreas - Ministero Salute (CUP_J33G13000210001); Wilhelm Sander Stiftung 2009.039.2; NIH grant P50 CA62924. See the Supplemental Information for further acknowledgments.