Journal article

Exploiting the Biginelli reaction: nitrogen-rich pyrimidine-based tercyclic alpha-helix mimetics

Zelong Lim, Peter J Duggan, Soo San Wan, Guillaume Lessene, Adam G Meyer, Kellie L Tuck

Tetrahedron | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2016


Awarded by NHMRC

Funding Acknowledgements

The authors acknowledge the support of the School of Chemistry, Monash University, and CSIRO Manufacturing; Biomedical Manufacturing Program. Z.L. gratefully acknowledges receipt of a Faculty of Science Dean's Postgraduate Research Scholarship and a top-up scholarship from CSIRO. We are also thankful to Dr. Craig Forsyth for X-ray crystal structure determination and the Victorian Partnership for Advanced Computing for access to their facilities for the molecular modelling component of this research. Part of this work was supported by an NHMRC (GNT1025138), the WEHI de Burgh Fellowship to GL, the Australian Cancer Research Foundation. Part of this work was made possible through Victorian State Government Operational Infrastructure Support and Australian Government NHMRC IRIISS (#361646).