Loss to follow-up in the Australian HIV Observational Database
Hamish McManus, Kathy Petoumenos, Katherine Brown, David Baker, Darren Russell, Tim Read, Don Smith, Lynne Wray, Michelle Giles, Jennifer Hoy, Andrew Carr, Matthew G Law
ANTIVIRAL THERAPY | INT MEDICAL PRESS LTD | Published : 2015
BACKGROUND: Loss to follow-up (LTFU) in HIV-positive cohorts is an important surrogate for interrupted clinical care, which can potentially influence the assessment of HIV disease status and outcomes. After preliminary evaluation of LTFU rates and patient characteristics, we evaluated the risk of mortality by LTFU status in a high-resource setting. METHODS: Rates of LTFU were measured in the Australian HIV Observational Database for a range of patient characteristics. Multivariate repeated measures regression methods were used to identify determinants of LTFU. Mortality by LTFU status was ascertained using linkage to the National Death Index. Survival following combination antiretroviral the..View full abstract
Awarded by US National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID)
The Australian HIV Observational Database is funded as part of the Asia Pacific HIV Observational Database, a programme of The Foundation for AIDS Research, amfAR, and is supported in part by a grant from the US National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID; grant number U01-AI069907) and by unconditional grants from Merck Sharp & Dohme, Gilead Sciences, Bristol-Myers Squibb, Boehringer Ingelheim, Janssen-Cilag and ViiV Healthcare. The Kirby Institute is funded by the Australian Government Department of Health and Ageing, and is affiliated with the Faculty of Medicine, UNSW Australia. The views expressed in this publication do not necessarily represent the position of the Australian Government.