Overview of Pediatric Peripheral Neuropathies

Abstract

The peripheral neuropathies are disorders affecting the axons, myelin, or Schwann cells of the peripheral nervous system. Peripheral neuropathy can manifest at any age, but its prevalence increases with increasing age. About one in 5000 children has a hereditary peripheral neuropathy (Charcot-Marie-Tooth disease), while acute acquired neuropathies (most commonly Guillain-Barré syndrome) affect about one in 120,000 children every year. While peripheral neuropathy is not a common condition in children, it can cause significant lifelong morbidity. A wide range of disorders can be associated with this disease, including hereditary, metabolic, inflammatory and acquired causes. This chapter review..