Book Chapter

Harnessing the Toxocara Genome to Underpin Toxocariasis Research and New Interventions

Robin B Gasser, Pasi K Korhonen, Xing-Quan Zhux, Neil D Young

ADVANCES IN PARASITOLOGY, VOL 91 | Advances in Parasitology | ELSEVIER ACADEMIC PRESS INC | Published : 2016

Abstract

Parasitic worms, such as flatworms (platyhelminths) and roundworms (nematodes), cause substantial morbidity and mortality in animals and people globally. The ascaridoid nematode Toxocara canis is a zoonotic parasite of socioeconomic significance worldwide. In humans, this worm causes toxocariasis (disease) mainly in underprivileged communities in both the developed and developing worlds. While reasonably well studied from clinical and epidemiological perspectives, little is understood about the molecular biology of T. canis, its relationship with its hosts and the disease that it causes. However, a recent report of the draft genome and transcriptomes of T. canis should underpin many fundamen..

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