Fenfluramine augmentation of clomipramine treatment of obsessive compulsive disorder

Abstract

Recently, much research interest has been directed to demonstrating a possible biological basis to obsessive compulsive disorder. In particular, dys-regulation in brain serotonin is suggested to be important. Two cases are described in which fenfluramine, a presynaptic 5 HT-releasing agent and 5HT-reuptake inhibitor was used to augment clomipramine treatment for OCD. © 1991 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.