Journal article
Developmental brain trajectories in children with ADHD and controls: A longitudinal neuroimaging study
TJ Silk, S Genc, V Anderson, D Efron, P Hazell, JM Nicholson, M Kean, CB Malpas, E Sciberras
BMC Psychiatry | Published : 2016
Abstract
Background: The symptom profile and neuropsychological functioning of individuals with Attention Deficit/Hyperactivity Disorder (ADHD), change as they enter adolescence. It is unclear whether variation in brain structure and function parallels these changes, and also whether deviations from typical brain development trajectories are associated with differential outcomes. This paper describes the Neuroimaging of the Children's Attention Project (NICAP), a comprehensive longitudinal multimodal neuroimaging study. Primary aims are to determine how brain structure and function change with age in ADHD, and whether different trajectories of brain development are associated with variations in outco..
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Awarded by Murdoch Children's Research Institute
Funding Acknowledgements
We would like to thank all of the many families and schools for their participation in this study. We would also like to acknowledge all staff and students for their contribution to this study, and Amanda Ng's contribution to the development of the QSM sequence. The study was funded by the National Medical Health and Research Council of Australia (NHMRC; project grant #1065895). The Children's Attention Project was as funded by an NHMRC project grant #1008522 and a grant from the Collier Foundation. The research was supported by the Murdoch Childrens Research Institute, The Royal Children's Hospital, The Royal Children's Hospital Foundation, Department of Paediatrics at The University of Melbourne and the Victorian Government's Operational Infrastructure Support Program. ES was supported by NHMRC Early Career (1037159) and Career Development (1110688) Fellowships. TS was supported by an NHMRC Career Development Award (1004637). VA was supported by an NHMRC Senior Practitioner Fellowship (1079478). JN was funded by the Australian Communities Foundation through the Roberta Holmes Chair for the Transition to Contemporary Parenthood Program (Coronella sub-fund).