Engineering anti-Lewis-Y hu3S193 antibodies with improved therapeutic ratio for radioimmunotherapy of epithelial cancers

Ingrid JG Burvenich; Fook-Thean Lee; Graeme J O'Keefe; Dahna Makris; Diana Cao; Sylvia Gong; Angela Rigopoulos; Laura C Allan; Martin W Brechbiel; Zhanqi Liu; Paul A Ramsland; Andrew M Scott

Journal article

Engineering anti-Lewis-Y hu3S193 antibodies with improved therapeutic ratio for radioimmunotherapy of epithelial cancers

Ingrid JG Burvenich, Fook-Thean Lee, Graeme J O'Keefe, Dahna Makris, Diana Cao, Sylvia Gong, Angela Rigopoulos, Laura C Allan, Martin W Brechbiel, Zhanqi Liu, Paul A Ramsland, Andrew M Scott

EJNMMI Research | SPRINGER HEIDELBERG | Published : 2016

DOI: 10.1186/s13550-016-0180-0

University of Melbourne Researchers

Zhanqi Liu Author Medicine - Austin Health

Graeme Joseph O'Keefe Author Physics

Andrew Scott Author Medicine - Austin Health

Paul Ramsland Author Surgery - Austin Health

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

This research was supported by National Health and Medical Research Council Project Grants 542512, 1030469, National Health and Medical Research Council Program grant 487922, National Health and Medical Research Council Practitioner Fellowship (A.M.S.), and in part by Ludwig Cancer Research, by funds from the Operational Infrastructure Support Program provided by the Victorian Government, and the Intramural Research Program of the NIH, National Cancer Institute, Centre for Cancer Research.