Synthesis and biological evaluation of 2-anilino-4-substituted-7H-pyrrolopyrimidines as PDK1 inhibitors

Nathan J O'Brien; Martin Brzozowski; Melissa J Buskes; Leslie W Deady; Belinda M Abbott

Journal article

Synthesis and biological evaluation of 2-anilino-4-substituted-7H-pyrrolopyrimidines as PDK1 inhibitors

Nathan J O'Brien, Martin Brzozowski, Melissa J Buskes, Leslie W Deady, Belinda M Abbott

Bioorganic & Medicinal Chemistry | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2014

DOI: 10.1016/j.bmc.2014.06.018

University of Melbourne Researchers

Martin Brzozowski Author Medical Biology (W.E.H.I.)

Grants

Funding Acknowledgements

The authors would like to thank Dr. Suzanne Cutts (La Trobe Institute for Molecular Science, La Trobe University) for her assistance with the biological assays and Dr. Jason Dang (Monash Institute of Pharmaceutical Sciences, Monash University) for HRMS analysis. N.J. O'Brien would like to thank the Australian government for financial support through the provision of an Australian Postgraduate Awards (APA) scholarship.