Anthelmintic activity of selected ethno-medicinal plant extracts on parasitic stages of Haemonchus contortus
Rasika Kumarasingha, Sarah Preston, Tiong-Chia Yeo, Diana SL Lim, Chu-Lee Tu, Enzo A Palombo, Jillian M Shaw, Robin B Gasser, Peter R Boag
PARASITES & VECTORS | BMC | Published : 2016
BACKGROUND: Parasitic roundworms (nematodes) cause substantial morbidity and mortality in livestock animals globally, and considerable productivity losses to farmers. The control of these nematodes has relied largely on the use of a limited number of anthelmintics. However, resistance to many of these these anthelmintics is now widespread, and, therefore, there is a need to find new drugs to ensure sustained and effective treatment and control into the future. METHODS: Recently, we developed a screening assay to test natural, plant extracts with known inhibitory effects against the free-living worm Caenorhabditis elegans. Using this assay, we assessed here the effects of the extracts on moti..View full abstract
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Funding from the National Health and Medical Research Council (NHMRC) of Australia is gratefully acknowledged. R.K. was awarded an Australian Postgraduate Award (APA) from the Australian Government via Monash University and Swinburne University of Technology.