Growth in North American white children with neurofibromatosis 1 (NF1)

J Szudek; P Birch; JM Friedman; W Burke; R Bennett; JM de Campos; B Korf; W Krause; K Uhas; M Niimura; Y Inaba; K North; J Ortenberg; V der Kaloustian; M Poyhonen; A Rubenstein; P Short; K Bove; S Stine; L Nicholson; R Tenconi; E Zackai; J Carey; D Viskochil; N Bochkov; E Schorry; S Tinschert; T Kelly; J Klein; E Piynick; A Colley; M Schulke; M Signorini; P Wolkenstein; A Danek

Journal article

Growth in North American white children with neurofibromatosis 1 (NF1)

J Szudek, P Birch, JM Friedman, W Burke, R Bennett, JM de Campos, B Korf, W Krause, K Uhas, M Niimura, Y Inaba, K North, J Ortenberg, V der Kaloustian, M Poyhonen, A Rubenstein, P Short, K Bove, S Stine, L Nicholson Show all

Journal of Medical Genetics | Published : 2000

DOI: 10.1136/jmg.37.12.933

Abstract

Objective - To analyse the distributions of and generate growth charts for stature and occipitofrontal circumference (OFC) in neurofibromatosis 1 (NF1) patients. Design - Cross sectional database survey. Setting - The National Neurofibromatosis Foundation International Database (NFDB) includes clinical information on NF1 patients from 14 participating centres in North America. Subjects - A total of 569 white, North American, NF1 patients, 55% female and 45% male. Main outcome measures - Stature and OFC measurements of NF1 patients were compared to age and sex matched population norms using z score standardisation and centile curves. Results - The distributions of stature and OFC are shifted ..

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